Multiscale plant modeling: from genome to phenome and beyond

Plant bioinformatics: from genome to phenome.

The vast quantities of diverse biological data generated by recent biotechnological advances have led to the development and evolution of the field of bioinformatics. This relatively new field facilitates both the analysis of genomic and postgenomic data and the integration of information from the related fields of transcriptomics, proteomics, metabolomics and phenomics. Such integration enable...

Multiscale Modeling: Beyond Non-Mereological Relations

Winsberg’s “handshaking” account of inter-model relations is a well-known theory of multiscale modeling in physical systems. Winsberg argues that relations among the component models in a multiscale modeling system are not related mereologically, but rather by empirically determined algorithms. I argue that while the handshaking account does demonstrate the existence of nonmereological relation...

Multiscale modeling of viscoelastic plant tissue

We present a multiscale method for the simulation of large viscoelastic deformations and show its applicability to biological tissue such as plant tissue. At the microscopic level we use a particle method to model the geometrical structure and basic properties of individual cells. The cell fluid, modeled as a viscoelastic fluid by means of Smoothed Particle Hydrodynamics (SPH) is enclosed in an...

Genome to Phenome Mapping in Apple Using Historical Data.

Apple ( X Borkh.) is one of the world's most valuable fruit crops. Its large size and long juvenile phase make it a particularly promising candidate for marker-assisted selection (MAS). However, advances in MAS in apple have been limited by a lack of phenotype and genotype data from sufficiently large samples. To establish genotype-phenotype relationships and advance MAS in apple, we extracted ...

American Heart Association Cardiovascular Genome-Phenome Study